Cyclic Bipyridine Glycosides from the Marine-Derived Actinomycete Actinoalloteichus cyanogriseus WH1-2216-6
Cyclic Bipyridine Glycosides from the Marine-Derived Actinomycete Actinoalloteichus cyanogriseus WH1-2216-6
复制标题
来自海洋源放线菌 Actinoalloteichuscyanogriseus WH1-2216-6 的环状联吡啶糖苷
DOI：
10.1021/ol202245s
复制
发表时间：
2011-11-18
期刊：
影响因子：
5.2
通讯作者：
Zhu, Weiming
中科院分区：
文献类型：
--
作者：
Fu, Peng;Liu, Peipei;Zhu, Weiming
从海洋来源的放线菌Actinoalloteichus cyanogriseus WH1-2216-6中分离到4个新的联吡啶糖苷类衍生物Cyanogrisides a -d(1-4)，它们是由具有头端中心和酮糖相邻羰基的苷元的邻近羟基生成的新型环状糖苷。通过光谱分析、x射线单晶衍射、CD光谱和化学方法对其中1 ~ 4的结构进行了鉴定。
Cyanogrisides A-D (1-4), four new glycosidic derivatives of bipyridine featuring a novel cyclic glycoside generated by vicinal hydroxyl groups of an aglycone with both the anomeric center and the adjacent carbonyl of a keto sugar, were isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus WH1-2216-6. The structures of 1-4 were elucidated by spectroscopic analysis, X-ray single crystal diffraction, CD spectra, and chemical methods.