On the Identification of the Survivor Average Causal Effect
On the Identification of the Survivor Average Causal Effect
复制标题
论幸存者平均因果效应的识别
DOI：
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发表时间：
2011
期刊：
影响因子：
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通讯作者：
Y. Uemura
中科院分区：
文献类型：
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作者：
Y. Chiba;M. Taguri;Y. Uemura
在随机试验中，结果需要大量的随访，参与者可能在试验完成前死亡。在这种情况下，对于在随访完成之前死亡的个体，结果不仅是缺失，而且是不确定的。一些作者将这种情况称为一种结果是<s:2>€œtruncated到死亡<e:2>€？[1,2]，将这种情况与仅仅因为数据收集不足而导致结果缺失的情况区分开来。在这些情况下，对每个治疗组中存活者的结果进行粗略的比较可能会产生误导性的结果，因为我们不再通过治疗后事件（生存）的条件来保持随机化，因此粗略的比较不是对同一人群比较不同治疗的比较，而是对不同人群的比较。
In randomized trials in which the outcome requires considerable follow-up, participants may die before the trial is complete. In such cases, for the individuals who die before follow-up is complete, the outcome is not simply missing, but is undefined. Some authors refer to this situation as one in which the outcome is “truncated by death� [1,2], to distinguish this scenario from cases in which the outcome is merely missing because of inadequate data collection. In these settings, a crude comparison of the outcome between those who survived in each treatment arm may give misleading results, because we no longer preserve randomization by conditioning on a post-treatment event (survival) and thus the crude comparison is not a comparison for the same population comparing different treatments, but a comparison of different populations.
影响因子：
5
作者：
Cole, Stephen R.;Hernan, Miguel A.
通讯作者：
Hernan, Miguel A.
影响因子：
2.1
作者：
Egleston, Brian L.;Scharfstein, Daniel O.;West, Sheila K.
通讯作者：
West, Sheila K.