Transganglionic transport of horseradish peroxidase in primary sensory neurons
Transganglionic transport of horseradish peroxidase in primary sensory neurons
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初级感觉神经元中辣根过氧化物酶的跨神经节转运
DOI：
10.1016/0304-3940(79)91474-5
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发表时间：
1979
影响因子：
2.5
通讯作者：
J. Ygge
中科院分区：
文献类型：
--
作者：
G. Grant;J. Arvidsson;B. Robertson;J. Ygge
将成年大鼠坐骨神经切断端暴露于辣根过氧化物酶（HRP）。使大鼠存活12 h-5 d。术后12-18 h，小背根神经节细胞比大背根神经节细胞标记更重。48-72小时后，更多的大细胞被强烈标记。从18 h开始，在同侧背角浅层有大量HRP标记，从48 h开始，在背角深层和薄束核也有大量HRP标记。重标记清楚地表明本方法用于作图目的的潜力。研究结果还表明，术后存活时间短可用于小细胞和纤维的选择性标记。
The cut end of the sciatic nerve of adult rats was exposed to horseradish peroxidase (HRP). The rats were allowed to survive for 12 h–5 days. 12–18 h postoperatively small dorsal root ganglion cells were more heavily labeled than large ones. After 48–72 h more large cells were intensely labeled. From 18 h onwards large amounts of HRP labeling was observed ipsilaterally in the superficial laminae of the dorsal horn, from 48 h also in deeper laminae and in the gracile nucleus. The heavy labeling clearly indicates the potential of the present approach for mapping purposes. The findings also indicate that short postoperative survivals can be used for rather selective marking of small cells and fibers.