Callosal window between prefrontal cortices: Cognitive interaction to retrieve long-term memory
Callosal window between prefrontal cortices: Cognitive interaction to retrieve long-term memory
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DOI：
10.1126/science.281.5378.814
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发表时间：
1998-08-07
期刊：
影响因子：
56.9
通讯作者：
Miyashita, Y
中科院分区：
文献类型：
--
作者：
Hasegawa, I;Fukushima, T;Miyashita, Y
A perceptual image can be recalled from memory without sensory stimulation. However, the neural origin of memory retrieval remains unsettled. To examine whether memory retrieval can be regulated by top-down processes originating from the prefrontal cortex, a visual associative memory task was introduced into the partial split-brain paradigm in monkeys. Long-term memory acquired through stimulus-stimulus association did not transfer via the anterior corpus callosum, a key part interconnecting prefrontal cortices. Nonetheless, when a visual cue was presented to one hemisphere, the anterior callosum could instruct the other hemisphere to retrieve the correct stimulus specified by the cue. Thus, although visual Long-term memory is stored in the temporal cortex, memory retrieval is under the executive control of the prefrontal cortex.
