Use of Rhodamine B as a Biomarker for Oral Plague Vaccination of Prairie Dogs
Use of Rhodamine B as a Biomarker for Oral Plague Vaccination of Prairie Dogs
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DOI：
10.7589/0090-3558-47.3.765
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发表时间：
2011-07-01
影响因子：
1.3
通讯作者：
Rocke, Tonie E.
中科院分区：
文献类型：
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作者：
Fernandez, Julia Rodriguez-Ramos;Rocke, Tonie E.
鼠疫菌口服疫苗可为草原犬鼠鼠疫的防治提供一种可行的途径。用于保护和公共卫生目的。生物标志物在野生动物疫苗接种计划中是有用的，以证明暴露于疫苗诱饵。罗丹明B（RB）作为口服鼠疫疫苗接种的潜在生物标志物进行了测试，因为它允许通过毛发、血液和粪便对动物进行非致死性采样。我们发现RB是一个合适的标记，用于诱饵摄取研究，
Oral vaccination against Yersinia pestis could provide a feasible approach for controlling plague in prairie dogs (Cynomys spp.) for conservation and public health purposes. Biomarkers are useful in wildlife vaccination programs to demonstrate exposure to vaccine baits. Rhodamine B (RB) was tested as a potential biomarker for oral plague vaccination because it allows nonlethal sampling of animals through hair, blood, and feces. We found that RB is an appropriate marker for bait uptake studies of