Urinary Cortisol Excretion Rates and Anxiety in Normal 1‐Year‐Old Infants
Urinary Cortisol Excretion Rates and Anxiety in Normal 1‐Year‐Old Infants
复制标题
正常 1 岁婴儿的尿皮质醇排泄率和焦虑程度
DOI：
10.1097/00006842-197705000-00003
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发表时间：
1977
影响因子：
3.3
通讯作者：
A. Vernadakis
中科院分区：
文献类型：
--
作者：
K. Tennes;K. Downey;A. Vernadakis
&NA;测定20例婴儿3天内每次排尿8小时的尿皮质醇排泄率。第一天作为对照。第二天，母亲离开婴儿一个小时，给他们施加压力。在第三天，孩子在母亲在场的情况下被新奇的玩具和社交刺激了一个小时。对照组和应激组的平均皮质醇排泄率无显著差异。皮质醇水平的变化显着更大的一天的压力比其他2天。应激后40 ~ 160 min分离焦虑评分与皮质醇分泌量呈正相关（r = 0.46，P < 0.01）。皮质醇水平在焦虑的婴儿中也有区别，他们是焦虑的，是孤僻的。皮质醇水平的改变与兴奋无关。
&NA; Urinary cortisol excretion rates were determined for each voiding during 8 hours on 3 days for 20 infants. The first day served as the control. On the second day stress was imposed by having the mother leave the infant for an hour. On a third day the child was stimulated by novel toys and socialization for an hour in the mother's presence. There was no significant difference between mean cortisol excretion rates on control and stress days. Variability in cortisol levels was significantly greater on the day of stress than on the other 2 days. Ratings of separation anxiety and levels of cortisol excreted 40 to 160 min after the imposed stress were positively correlated (r = 0.46, P < 0.01). Cortisol levels also differentiated between anxious infants who were agitated from those who were withdrawn. No altered levels of cortisol were associated with excitement.