Increasing incidence and improving survival of oral tongue squamous cell carcinoma
Increasing incidence and improving survival of oral tongue squamous cell carcinoma
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DOI：
10.1038/s41598-020-64748-0
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发表时间：
2020-05-12
影响因子：
4.6
通讯作者：
Kim, Jin Ho
中科院分区：
文献类型：
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作者：
Kim, Yi-Jun;Kim, Jin Ho
我们评估了头颈部鳞状细胞癌（HNSCC）的发病率、相对生存率（RS）和条件生存率（CS）的变化，重点是口腔舌鳞状细胞癌（OTSCC）。从1976年至2015年的74680例HNSCC患者的数据来自监测，流行病学和最终结果数据库。分析了5个解剖部位及其子部位。计算发病率的年变化百分比（APC）。RS和CS在四十年内进行了比较。采用多元回归分析评价RS的校正风险比（aHR）。OTSCC发病率较1976年下降（APC=-0.76，P
We evaluated changes in incidence, relative survival (RS), and conditional survival (CS) of head and neck squamous cell carcinoma (HNSCC), focusing on oral tongue squamous cell carcinoma (OTSCC). Data of 74 680 HNSCC patients from 1976 to 2015 were obtained from the Surveillance, Epidemiology, and End Results database. Five anatomical sites and their subsites were analyzed. Annual percent change (APC) of incidence was calculated. RS and CS were compared across the four decades. Adjusted hazard ratios (aHRs) of RS were evaluated using multivariate regression. OTSCC incidence decreased from 1976 (APC=-0.76, P