The burden of early exposure to malaria in the United States, 1850-1860: Malnutrition and immune disorders
The burden of early exposure to malaria in the United States, 1850-1860: Malnutrition and immune disorders
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DOI：
10.1017/s0022050707000472
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发表时间：
2007-12-01
影响因子：
2.1
通讯作者：
Hong, Sok Chul
中科院分区：
文献类型：
--
作者：
Hong, Sok Chul
这篇文章使用19世纪的证据来计算早期暴露在疟疾肆虐的环境中对美国人营养状况和免疫系统的影响。我通过使用疟疾与气候和地理特征等环境因素之间的相关性来估计19世纪50年代感染疟疾的风险。研究表明，由于营养不良，早年生活在疟疾流行县的联邦军队新兵入伍时矮了1.1英寸，而在美国内战期间，由于免疫系统紊乱，他们比那些来自无疟疾地区的人更容易感染疾病。
This article uses nineteenth-century evidence to calculate the impact of early exposure to malaria-ridden environments on nutritional status and the immune system in America. I estimate the risk of contracting malarial fevers in the 1850s by using correlations between malaria and environmental factors such as climate and geographical features. The study demonstrates that Union Army recruits who spent their early years in malaria-endemic counties were 1.1 inches shorter at enlistment due to malnutrition and were 13 percent more susceptible to infections during the U.S. Civil War as a result of immune disorders than were those from malaria-free regions.