Environmentally benign and energy efficient methodology for condensation: an interesting facet to the classical Perkin reaction
Environmentally benign and energy efficient methodology for condensation: an interesting facet to the classical Perkin reaction
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DOI：
10.1039/c0gc00712a
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发表时间：
2011-01
期刊：
影响因子：
9.8
通讯作者：
Poonam Mahadev Pawar;K. J. Jarag;G. Shankarling
中科院分区：
文献类型：
--
作者：
Poonam Mahadev Pawar;K. J. Jarag;G. Shankarling
本文报道了以氯化胆碱和尿素为基础的可生物降解的低共熔溶剂（DES），通过Perkin反应合成肉桂酸及其衍生物。该反应在温和条件下进行，不需要使用额外的催化剂，产率较高。具有一致活性的溶剂的易于回收和可重复使用性使得该方法高效且环境友好。这种方法也是节能的，易于操作。
We have reported use of biodegradable deep eutectic solvent (DES) based on choline chloride and urea, for the synthesis of cinnamic acid and its derivatives viaPerkin reaction. The reaction proceeds efficiently under mild condition without use of additional catalyst with better yields. Ease of recovery and reusability of solvent with consistent activity makes this method efficient and environmentally benign. This method is also energy efficient and easy to handle.