TRIDIMENSIONAL STUDY OF THE DEEP CORTEX OF THE RAT LYMPH-NODE .3. MORPHOLOGY OF THE DEEP CORTEX UNITS
TRIDIMENSIONAL STUDY OF THE DEEP CORTEX OF THE RAT LYMPH-NODE .3. MORPHOLOGY OF THE DEEP CORTEX UNITS
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DOI：
10.1002/ar.1091990206
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发表时间：
1981-01-01
影响因子：
--
通讯作者：
SAINTEMARIE, G
中科院分区：
文献类型：
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作者：
BELISLE, C;SAINTEMARIE, G
大鼠淋巴结的深皮层由半圆形单元组成，其中一些单元部分融合成复合体。每个单元都以传入淋巴管的开口为中心，节点深部皮质的拓扑结构与其传入淋巴管的开口的分布模式相关。在这里，深层皮质单元的形态得到了阐明，特别是其网状框架、淋巴窦和毛细血管后微静脉网络。通过三维重建从不同位置分析大鼠节点。每个单元由一个中心和一个外围组成，根据其形态特征彼此区分。中心几乎没有网状纤维，外围呈现致密的纤维框架。外周是一个单位的大多数毛细血管后微静脉的集中部位，并且包含淋巴窦，特别是，淋巴窦通常载有小淋巴细胞。虽然这两个区域主要由小淋巴细胞组成，但外围这些细胞的浓度通常低于中心。该中心显然是细胞滞留和增殖的场所；外周是淋巴细胞快速迁移进出该单位的部位。
The deep cortex of the rat lymph node is made up of semi-rounded units, some of which are partially fused into complexes. Each unit is centered on the opening(s) of an afferent lymphatic vessel, the topographical organization of the deep cortex of a node correlating with the distribution pattern of the opening(s) of its afferent lymphatic(s). Here, the morphology of the deep cortex unit was clarified, particularly with regard to its reticular framework, its lymphatic sinuses and its network of postcapillary venules. Rat nodes were analyzed from various locations by tridimensional reconstruction. Each unit is formed of a center and a periphery, distinguishable from one another on the basis of their morphological features. The center is nearly devoid of reticular fibers, the periphery exibits a dense framework of fibers. The periphery is the site of concentration of most postcapillary venules of a unit and contains lymphatic sinuses which, peculiarly, are often loaded with small lymphocytes. While both regions are populated mainly by small lymphocytes, the periphery usually contains a lower concentration of these cells than the center. The center evidently is a site of cellular retention and proliferation; the periphery is a site of rapid lymphocyte migration in and out of the unit.