PlantTFDB 4.0: toward a central hub for transcription factors and regulatory interactions in plants.
PlantTFDB 4.0: toward a central hub for transcription factors and regulatory interactions in plants.
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PlantTFDB 4.0:成为植物转录因子和调控相互作用的中心枢纽。
DOI:
10.1093/nar/gkw982
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发表时间:
2017-01-04
影响因子:
14.9
通讯作者:
Gao G
中科院分区:
文献类型:
--
作者:
Jin J;Tian F;Yang DC;Meng YQ;Kong L;Luo J;Gao G
With the goal of providing a comprehensive, high-quality resource for both plant transcription factors (TFs) and their regulatory interactions with target genes, we upgraded plant TF database PlantTFDB to version 4.0 (http://planttfdb.cbi.pku.edu.cn/). In the new version, we identified 320 370 TFs from 165 species, presenting a more comprehensive genomic TF repertoires of green plants. Besides updating the pre-existing abundant functional and evolutionary annotation for identified TFs, we generated three new types of annotation which provide more directly clues to investigate functional mechanisms underlying: (i) a set of high-quality, non-redundant TF binding motifs derived from experiments; (ii) multiple types of regulatory elements identified from high-throughput sequencing data; (iii) regulatory interactions curated from literature and inferred by combining TF binding motifs and regulatory elements. In addition, we upgraded previous TF prediction server, and set up four novel tools for regulation prediction and functional enrichment analyses. Finally, we set up a novel companion portal PlantRegMap (http://plantregmap.cbi.pku.edu.cn) for users to access the regulation resource and analysis tools conveniently.
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DOI:
10.1093/bioinformatics/btr064
发表时间:
2011-04-01
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Grant CE;Bailey TL;Noble WS
通讯作者:
Noble WS
DOI:
10.1073/pnas.1316278111
发表时间:
2014-02-11
影响因子:
11.1
作者:
Franco-Zorrilla, Jose M.;Lopez-Vidriero, Irene;Solano, Roberto
通讯作者:
Solano, Roberto
影响因子:
14.9
作者:
Matys V;Kel-Margoulis OV;Fricke E;Liebich I;Land S;Barre-Dirrie A;Reuter I;Chekmenev D;Krull M;Hornischer K;Voss N;Stegmaier P;Lewicki-Potapov B;Saxel H;Kel AE;Wingender E
通讯作者:
Wingender E
影响因子:
14.9
作者:
Mathelier A;Fornes O;Arenillas DJ;Chen CY;Denay G;Lee J;Shi W;Shyr C;Tan G;Worsley-Hunt R;Zhang AW;Parcy F;Lenhard B;Sandelin A;Wasserman WW
通讯作者:
Wasserman WW
影响因子:
10.7
作者:
Jin J;He K;Tang X;Li Z;Lv L;Zhao Y;Luo J;Gao G
通讯作者:
Gao G