Palliative Care and Characterization of Symptoms in Patients Undergoing Cytoreductive Surgery/Hyperthermic Intraperitoneal Chemotherapy.
Palliative Care and Characterization of Symptoms in Patients Undergoing Cytoreductive Surgery/Hyperthermic Intraperitoneal Chemotherapy.
复制标题
接受细胞减灭手术/腹腔高温化疗患者的姑息治疗和症状特征。
DOI：
10.1016/j.jss.2022.11.061
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Eng,OliverS
中科院分区：
文献类型：
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作者：
Sneider,AbigailP;Dhiman,Ankit;Sood,Divya;Ong,Cecilia;Tun,Sandy;Malec,Monica;Levine,Stacie;Turaga,KiranK;Eng,OliverS
前言晚期癌症患者的姑息治疗与改善症状管理和生活质量(QOL)有关。接受细胞减灭术(CRS)和热疗腹膜内化疗(HIPEC)的腹膜转移瘤患者经常出现影响生活质量的症状。在这一背景下，我们对姑息治疗者和手术提供者阐明的症状进行了表征和比较。方法从回顾数据库中确定2016-2020年在三级护理中心同时接受手术肿瘤学和姑息治疗提供者治疗的CRS/HIPEC患者。记录和分析外科肿瘤学和姑息治疗中与生活质量相关的症状。结果共118名患者纳入研究。最常见的原发组织是阑尾(36.4%)和结直肠(28.8%)。姑息治疗最常见的症状是疼痛(60.2%)和疲劳(54.2%)。记录的症状中位数在姑息治疗笔记中为3(2，5)，在外科肿瘤学笔记中为2(0，3)(P<；0.001)。姑息治疗提供者记录的大多数症状在统计上比外科肿瘤提供者更多。结论接受CRS/HIPEC的患者经历了各种与生活质量相关的症状。姑息护理提供者比外科肿瘤学提供者引起更多的症状。在这一具有挑战性的患者群体中，需要更多的研究来探索对围手术期姑息治疗结果的影响。
IntroductionPalliative care for advanced cancer patients has been associated with improvements in symptom management and quality of life (QoL). Patients with peritoneal metastases undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) often report symptoms adversely affecting QoL. We characterized and compared symptoms elucidated by palliative careversussurgical providers in this setting.MethodsCRS/HIPEC patients who saw both surgical oncology and palliative care providers from 2016 to 2020 at a tertiary care center were identified from a retrospective database. Documentation of QoL-associated symptoms in surgical oncology and palliative care visits was recorded and analyzed.ResultsA total of 118 patients were included in this study. The most common primary histologies were appendiceal (36.4%) and colorectal (28.8%). Symptoms most frequently reported by palliative care were pain (60.2%) and fatigue (54.2%). The median number of symptoms documented was three (2, 5) in palliative care notes and two (0, 3) in surgical oncology notes (P< 0.001). Palliative care providers documented most symptoms statistically more frequently than surgical oncology providers.ConclusionsPatients who underwent CRS/HIPEC experienced various QoL-associated symptoms. Palliative care providers elicited more symptoms than surgical oncology providers. Additional studies are needed to explore the impact on outcomes of perioperative palliative care in this challenging patient population.