Association of swine vertnin (VRTN) gene with production traits in Duroc pigs improved using a closed nucleus breeding system
Association of swine vertnin (VRTN) gene with production traits in Duroc pigs improved using a closed nucleus breeding system
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DOI：
10.1111/j.1740-0929.2012.01066.x
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发表时间：
2013-01-01
影响因子：
2
通讯作者：
Awata, Takashi
中科院分区：
文献类型：
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作者：
Hirose, Kensuke;Mikawa, Satoshi;Awata, Takashi
Vertnin（VRTN）基因定位于猪第7号染色体上，与猪脊椎数目的变异有关。猪的脊椎数与体尺相关，许多研究表明体长与产肉性状之间存在相关性。因此，我们分析了VRTN基因型与杜洛克猪生产性能和体组成性状的关系。背最长肌肌内脂肪含量（IMF）与VRTN基因型显著相关。野生型个体的平均IMF（Wt/Wt）（5.22%）大于Wt/Q（4.99%）和Q/Q（4.79%）。此外，多性状动物模型的最佳线性无偏预测表明，Wt等位基因对IMF育种值有积极的影响。未观察到VRTN基因型与其他生产性状之间的关联。VRTN基因型与BL相关。Q/Q基因型个体的体长（100.0cm）高于Wt/Q基因型（99.5cm）和Wt/Wt基因型（98.9cm）。这些结果表明，除了维持适当的背膘厚度值，VRTN有可能作为IMF的遗传标记。
Vertnin (VRTN) is involved in the variation of vertebral number in pigs and it is located on Sus scrofa chromosome 7. Vertebral number is related to body size in pigs, and many reports have suggested presence of an association between body length (BL) and meat production traits. Therefore, we analyzed the relationship between the VRTN genotype and the production and body composition traits in purebred Duroc pigs. Intramuscular fat content (IMF) in the Longissimus muscle was significantly associated with the VRTN genotype. The mean IMF of individuals with the wild-type genotype (Wt/Wt) (5.22%) was greater than that of individuals with the Wt/Q (4.99%) and Q/Q genotypes (4.79%). In addition, a best linear unbiased predictor of multiple traits animal model showed that the Wt allele had a positive effect on the IMF breeding value. No associations were observed between the VRTN genotype and other production traits. The VRTN genotype was related to BL. The Q/Q genotype individuals (100.0cm) were longer than individuals with the Wt/Q (99.5cm) and Wt/Wt genotypes (98.9cm). These results suggest that in addition to the maintenance of an appropriate backfat thickness value, VRTN has the potential to act as a genetic marker of IMF.