Activity of the novel fungicide oxathiapiprolin against plant-pathogenic oomycetes
Activity of the novel fungicide oxathiapiprolin against plant-pathogenic oomycetes
复制标题
新型杀菌剂 oxathiapiprolin 对植物病原卵菌的活性
DOI：
10.1002/ps.4189
复制
发表时间：
2016-08-01
影响因子：
4.1
通讯作者：
Liu, Xili
中科院分区：
文献类型：
--
作者：
Miao, Jianqiang;Dong, Xue;Liu, Xili
奥硫匹普林是杜邦公司于2007年发现和开发的第一种哌啶基噻唑异恶唑啉类杀菌剂。尽管据报道oxathiapiprolin对植物病原性卵菌（例如Peronospora belbahrii、Phytophthora nicotianae和Ph. capsici）具有高活性，但对其对其他植物病原性卵菌的有效性及其保护和治疗特性知之甚少。结果oxathiapiprolin对所有测试的植物病原性卵菌均表现出显着的抑制活性，EC 90值范围为0.14至3.36 x 10（-3）μ g mL（-1），腐霉属Py除外。aphanidermatum和Py. deliense。此外，低至10 μ g/mL（-1）的剂量也会抑制辣椒疫霉游动孢子的释放和运动性，而黄瓜霜霉病菌的菌丝发育和孢子囊产生则受到EC 50的抑制，分别为3.10 x 10（-4）和5.17 x 10（-4）μ g/mL（-1）。还发现oxathiapiprolin在温室条件下和田间试验中对辣椒Ph. capsici感染的发展表现出保护和治疗活性。结论本研究表明，新型杀菌剂oxathiapiprolin对一系列农业上重要的植物病原卵菌，包括疫霉属，荔枝霜疫霉（Peronophythora litchii）、葡萄生霜霉病（Plasmopara viticola）、Pe. parasitica，Ps. cubensis和Py.最后一个(c)2015年化学工业协会
BACKGROUNDOxathiapiprolin was the first of the piperidinyl thiazole isoxazoline class of fungicides to be discovered and developed by DuPont in 2007. Although oxathiapiprolin has been reported to have high activity against plant-pathogenic oomycetes, such as Peronospora belbahrii, Phytophthora nicotianae and Ph. capsici, little is known about its effectiveness against other plant-pathogenic oomycetes and its protective and curative properties.RESULTSOxathiapiprolin exhibited substantial inhibitory activity against all of the plant-pathogenic oomycetes tested, with EC90 values ranging from 0.14 to 3.36 x 10(-3) mu g mL(-1), except the Pythium species Py. aphanidermatum and Py. deliense. Furthermore, doses as low as 10 mu g mL(-1) were found to inhibit zoospore release and motility in Ph. capsici, while the mycelial development and sporangial production of Pseudoperonospora cubensis were restrained by an EC50 of 3.10 x 10(-4) and 5.17 x 10(-4) mu g mL(-1) respectively. It was also found that oxathiapiprolin exhibited both protective and curative activity against the development of Ph. capsici infection in pepper plants under greenhouse conditions and in field tests.CONCLUSIONThe present study demonstrated that the novel fungicide oxathiapiprolin exhibits strong inhibitory activity against a range of agriculturally important plant-pathogenic oomycetes, including Phytophthora spp., Peronophythora litchii, Plasmopara viticola, Pe. parasitica, Ps. cubensis and Py. ultimum. (c) 2015 Society of Chemical Industry