The development of the length of the temporal window of integration for rapidly presented auditory information as indexed by MMN.
The development of the length of the temporal window of integration for rapidly presented auditory information as indexed by MMN.
复制标题
MMN 索引的快速呈现听觉信息的积分时间窗口长度的发展。
DOI：
10.1016/j.clinph.2005.03.008
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发表时间：
2005
期刊：
影响因子：
--
通讯作者：
Sussman,Elyse
中科院分区：
文献类型：
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作者：
Wang,Wenjung;Datta,Hia;Sussman,Elyse
在成年人中，将连续的听觉刺激整合成单一感知的时间窗的长度估计小于200 ms。方法采用改良的听觉oddball范式，以快速（150- 400 ms）的起始-起始速度记录两组5-8岁和9-11岁儿童和一组成人的脑电图，观察儿童整合窗的发展，并与成人比较。结果：1.事件相关脑电位（ERP）的整合时间窗（TWI）长度成人（<200 ms）短于大龄儿童（9-11岁<300 ms）和低龄儿童（5-8岁<350 ms）。此外，ERP成分的潜伏期和振幅的年龄相关性的变化被发现。结论本结果表明，一般的成熟发展的听觉诱发电位，也是一个特定的成熟过程，在听觉皮层的时间编码的信息。重要意义快速刺激呈现率可以成功地用于学龄儿童的听觉过程的神经机制研究。
OBJECTIVEThe length of the temporal window integrating successive auditory stimuli into unitary percepts has been estimated to be less than 200ms in adults. The aim of the study was to investigate the development of the integrating window in children to determine whether it is similar to young adults.METHODSA modified auditory oddball paradigm was presented at a rapid (150–400ms) onset-to-onset pace during recording of electroencephalogram in two groups of children (aged 5–8 and 9–11 years) and one group of adults. Latencies and amplitudes of the P1, N1, and the mismatch negativity (MMN) components of event-related brain potentials (ERPs) were measured.RESULTSThe length of the temporal window of integration (TWI) was shorter in adults (<200ms) than older children (<300ms in 9–11-year-olds) and younger children (<350ms in the 5–8-year-olds). In addition, age-related changes were found in the latency and amplitude of the ERP components.CONCLUSIONSThe results demonstrate a general maturational development of the auditory evoked potentials and also a specific maturational process for temporal encoding of information in auditory cortex.SIGNIFICANCERapid stimulus presentation rates can be successfully used in school-aged children to study neural mechanisms of auditory processes.