PREMATURITY AND PERINATAL-MORTALITY IN PREGNANCIES COMPLICATED BY MATERNAL CHLAMYDIA-TRACHOMATIS INFECTIONS

PREMATURITY AND PERINATAL-MORTALITY IN PREGNANCIES COMPLICATED BY MATERNAL CHLAMYDIA-TRACHOMATIS INFECTIONS
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DOI:
10.1001/jama.247.11.1585
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发表时间:
1982-01-01
影响因子:
120.7
通讯作者:
HOLMES, KK
HOLMES, KK
中科院分区:
医学1区
文献类型:
--
作者:
MARTIN, DH;KOUTSKY, L;HOLMES, KK

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在一项前瞻性研究中,妊娠期沙眼衣原体感染、C.在268例孕19周前检查的妇女中,18例(6.7%)从宫颈内膜分离出沙眼。受感染的妇女明显比未受感染的妇女年轻,未婚、接受公共援助和首次怀孕的妇女明显更多。在从妊娠19周到分娩的妇女中,产前衣原体感染者的平均妊娠期明显缩短。死产或新生儿死亡发生在6(33%)的18例感染妇女的妊娠与8(3.4%)的238例未感染妇女的妊娠随访从妊娠第19周到分娩。在年龄、婚姻状况、社会经济状况、妊娠顺序和种族相匹配的未感染对照组中,衣原体感染妇女的死产或新生儿死亡率高出10倍。
In a prospective study of morbidity associated with C. trachomatis infections during pregnancy, C. trachomatis was isolated from the endocervix of 18 (6.7%) of 268 women examined before 19 wk gestation. Infected women were significantly younger than noninfected women, and significantly more often unmarried, supported by public assistance and pregnant for the 1st time. Among women followed up from 19 wk gestation until delivery, the mean duration of gestation was significantly shorter for those with antepartum chlamydial infection. Stillbirth or neonatal death occurred in 6 (33%) of the 18 pregnancies of infected women compared with 8 (3.4%) of the 238 pregnancies of noninfected women followed up from the 19th wk of gestation through delivery. Stillbirth or neonatal death occurred 10 times more often among Chlamydia-infected women than among uninfected controls matched for age, marital status, socioeconomic status, pregnancy order and race.