Short- and Long-Term Cause of Death in Patients Treated With Primary PCI for STEMI
Short- and Long-Term Cause of Death in Patients Treated With Primary PCI for STEMI
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DOI：
10.1016/j.jacc.2014.08.037
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发表时间：
2014-11-18
影响因子：
24
通讯作者：
Jorgensen, Erik
中科院分区：
文献类型：
--
作者：
Pedersen, Frants;Butrymovich, Vitalij;Jorgensen, Erik
背景在接受直接经皮冠状动脉介入治疗（PCI）的患者中，短期死亡率已经被彻底研究，而ST段抬高型心肌梗死（STEMI）患者的长期死亡原因仍然未知。和公共疾病和死亡原因登记处与一个准确的记录链接，用于跟踪时间和死亡原因在2,804例连续STEMI患者（年龄63 +/- 13岁，72%男性）接受直接PCI治疗。在总计13，447患者年中，717例患者死亡。前30天内死亡的主要原因是心源性休克和心脏骤停后缺氧性脑损伤。年龄、罪犯血管的大小和流量、心力衰竭和糖尿病的存在是死亡率的独立预测因素。30天后，年心源性死亡率为
BACKGROUND Short-term mortality has been studied thoroughly in patients undergoing primary percutaneous coronary intervention (PCI), whereas long-term cause of death in patients with ST-segment elevation myocardial infarction (STEMI) remains unknown.OBJECTIVES The goal of this study was to describe the association between time and cause of death in patients with STEMI undergoing primary PCI.METHODS A centralized civil registration system, patient files, and public disease and death cause registries with an accurate record linkage were used to trace time and cause of death in 2,804 consecutive patients with STEMI (age 63 +/- 13 years, 72% males) treated with primary PCI.RESULTS Patients were followed up for a median of 4.7 years. During a total of 13,447 patient-years, 717 patients died. Main causes of death within the first 30 days were cardiogenic shock and anoxic brain injury after cardiac arrest. Age, culprit vessel size and flow, and the presence of heart failure and diabetes were independent predictors of mortality. After 30 days, the annual cardiac mortality rate was