Muscle synergies after stroke are correlated with perilesional high gamma.
Muscle synergies after stroke are correlated with perilesional high gamma.
复制标题
DOI：
10.1002/acn3.368
复制
发表时间：
2016-12
影响因子：
5.3
通讯作者：
Ganguly K
中科院分区：
文献类型：
--
作者：
Godlove J;Gulati T;Dichter B;Chang E;Ganguly K
运动可以被分解成称为“肌肉协同作用”的模块。中风后，异常协同作用与运动受损有关;然而，其神经基础尚不清楚。在一个单一的主题，我们研究了如何从病灶周围皮质皮质的皮质电图信号与协同作用。测得的协同作用包含了正常和异常模式的混合，并在过去的工作中所描述的非常相似。有趣的是，我们发现正常和异常的协同作用都与病灶周围的高γ相关。考虑到高伽马和皮质尖峰之间的联系，我们的研究结果表明，病灶周围尖峰可能组织中风后的协同作用。
Movements can be factored into modules termed “muscle synergies”. After stroke, abnormal synergies are linked to impaired movements; however, their neural basis is not understood. In a single subject, we examined how electrocorticography signals from the perilesional cortex were associated with synergies. The measured synergies contained a mix of both normal and abnormal patterns and were remarkably similar to those described in past work. Interestingly, we found that both normal and abnormal synergies were correlated with perilesional high gamma. Given the link between high gamma and cortical spiking, our results suggest that perilesional spiking may organize synergies after stroke.