Superselective pseudo-continuous arterial spin labeling angiography
Superselective pseudo-continuous arterial spin labeling angiography
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DOI：
10.1016/j.ejrad.2015.05.034
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发表时间：
2015-09-01
影响因子：
3.3
通讯作者：
Helle, Michael
中科院分区：
文献类型：
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作者：
Jensen-Kondering, Ulf;Lindner, Thomas;Helle, Michael
目的：与临床使用的飞行时间（TOF）MRA相比，评价一种基于超选择性伪连续动脉自旋标记（ASL）的新型非对比增强血管选择性磁共振血管造影（MRA）方法在颅内动脉形态评估中的实用性。材料和方法：三组选择性ASL血管造影（右和左颈内动脉，基底动脉）以及一个TOF数据集在临床1.5T系统上从包括在本研究中的五个志愿者中的每一个获得。由两名放射科医师独立评价和分析动脉段的描绘及其描绘。此外，ASL血管造影方法在两名患有动静脉畸形（AVM）的患者中进行，以说明在临床环境中的潜在应用。在两种血管造影技术中，颅内动脉及其段（远端分支可达大脑前动脉的A5段、大脑中动脉的M8段，和大脑后动脉的P5段）连续描绘，具有良好的阅片者间一致性（kappa > 0.81）。在AVM患者中，TOF血管造影的重建图像显示了与超选择ASL血管造影相似的AVM大小和形状信息。此外，所获得的ASL血管造影片的选定的血管允许评估的血液供应的单独标记的动脉的AVM，也可以通过数字减影angiography.Conclusion：超选择ASL血管造影术，使它能够可视化选定的血管的动脉树，从而提供有关的大血管的血液供应和流动领域的颅内动脉的信息。与临床使用的TOF血管造影术相比，在动脉段的识别和描绘方面实现了相似的图像质量。超选择ASL血管造影术在两名AVM患者中的初步应用证明了收集有关供血血管和血液供应的其他重要信息的能力。(C)2015爱思唯尔爱尔兰有限公司版权所有。
Purpose: To evaluate the utility of a novel non-contrast enhanced, vessel-selective magnetic resonance angiography (MRA) approach based on superselective pseudo-continuous arterial spin labeling (ASL) for the morphologic assessment of intracranial arteries when compared to a clinically used time-of-flight (TOF) MRA.Materials and methods: Three sets of selective ASL angiographies (right and left internal carotid artery, basilar artery) as well as one TOF data set were obtained from each of the five volunteers included in this study on a clinical 1.5T system. The depiction of arterial segments as well as their delineation was evaluated and independently analyzed by two radiologists. Additionally, the ASL angiography approach was performed in two patients suffering from arterio-venous malformations (AVM) in order to illustrate potential applications in a clinical setting.Results: In both angiography techniques, intracranial arteries and their segments (distal branches up to A5 segments of the anterior cerebral arteries, M8 segments of the middle cerebral arteries, and P5 segments of the posterior cerebral arteries) were continuously depicted with excellent inter-reader agreement (kappa > 0.81). In AVM patients, reconstructed images of the TOF angiography presented similar information about the size and shape of the AVM as did superselective ASL angiography. In addition, the acquired ASL angiograms of selected vessels allowed assessing the blood supply of individually labeled arteries to the AVM which could also be confirmed by digital subtraction angiography.Conclusion: Superselective ASL angiography makes it possible to visualize arterial trees of selected vessels, thereby, providing information about the macrovascular blood supply and flow territories of intracranial arteries. Similar image quality is achieved when compared to clinically used TOF angiography with respect to the identification and delineation of arterial segments. Initial application of superselective ASL angiography in two patients with AVM's demonstrates the ability to gather additional important information about feeding vessels and blood supply. (C) 2015 Elsevier Ireland Ltd. All rights reserved.