Imaging Follow-Up of Nonsurgical Therapies for Lung Cancer: AJR Expert Panel Narrative Review.
Imaging Follow-Up of Nonsurgical Therapies for Lung Cancer: AJR Expert Panel Narrative Review.
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DOI：
10.2214/ajr.23.29104
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发表时间：
2023-04
期刊：
影响因子：
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通讯作者：
D. Murphy;M. Mayoral;A. Larici;M. Ginsberg;G. Cicchetti;F. Fintelmann;E. Marom;M. Truong;R. Gill
中科院分区：
文献类型：
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作者：
D. Murphy;M. Mayoral;A. Larici;M. Ginsberg;G. Cicchetti;F. Fintelmann;E. Marom;M. Truong;R. Gill
肺癌仍然是全世界癌症相关死亡的最常见原因。在过去的十年中，随着肺癌筛查计划的实施以及手术和非手术治疗的进步，肺癌患者的生存率有所提高，这些患者接受的影像学检查数量也有所增加。然而，大多数诊断为肺癌的患者由于共病或诊断时的晚期而不接受手术切除。非手术治疗持续发展，全身和靶向治疗的范围不断扩大，这与此类治疗后随访检查中遇到的成像结果的演变有关（例如，关于治疗后变化、治疗并发症和复发性肿瘤）。本AJR专家小组叙述性综述描述了肺癌非手术治疗的现状及其预期和非预期的影像学表现，为放射科医生提供此类治疗后影像学评估的指导，主要关注非小细胞肺癌。涵盖的治疗包括全身治疗（常规化疗、靶向治疗和免疫治疗）、放疗和热消融。
Lung cancer continues to be the most common cause of cancer-related death worldwide. In the past decade, with the implementation of lung cancer screening programs and advances in surgical and nonsurgical therapies, the survival of patients with lung cancer has increased, as has the number of imaging studies that these patients receive. However, most patients diagnosed with lung cancer do not undergo surgical resection due to comorbid disease or advanced stage at diagnosis. Nonsurgical therapies have continued to evolve, with a growing range of systemic and targeted therapies, associated with evolution in the imaging findings encountered on follow-up examinations after such therapies (e.g., with respect to posttreatment changes, treatment complications, and recurrent tumor). This AJR Expert Panel Narrative Review describes the current status of nonsurgical therapies for lung cancer and their expected and unexpected imaging manifestations, to provide guidance to radiologists regarding imaging assessment after such therapies, focusing mainly on nonsmall cell lung cancer. Covered therapies include systemic therapy (conventional chemotherapy, targeted therapy, and immunotherapy), radiotherapy, and thermal ablation.