Surface-Based Body Shape Index and Its Relationship with All-Cause Mortality.
Surface-Based Body Shape Index and Its Relationship with All-Cause Mortality.
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DOI：
10.1371/journal.pone.0144639
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发表时间：
2015
期刊：
影响因子：
3.7
通讯作者：
Adjeroh D
中科院分区：
文献类型：
--
作者：
Rahman SA;Adjeroh D
肥胖是一个全球性的公共卫生挑战。例如，在美国，肥胖率仍然很高，超过三分之一的成年人口，而超过三分之二的人肥胖或超重。肥胖与各种健康问题有关，如糖尿病、心血管疾病、抑郁症、某些形式的癌症、睡眠呼吸暂停、骨关节炎等。身体质量指数(BMI)是最著名的肥胖衡量标准之一。然而，BMI有严重的局限性，例如，它无法捕捉瘦质量和脂肪组织的分布，这是更好地预测糖尿病和心血管疾病的指标，以及它与死亡风险的曲线(“U形”)关系。其他人体测量方法及其与肥胖的关系也被研究过，每种方法都有其优点和局限性。在这项工作中，我们引入了一种新的人体测量方法(称为基于表面的身体形状指数，SBSI)，它同时考虑了体型和体型，并评估了它作为全因死亡率预测因子的表现。我们分析了11,808名受试者(年龄18-85岁)的数据，这些数据来自1999年至2004年的国家健康和人类营养检查调查(NHANES)，并对8年的死亡率进行了跟踪调查。在此基础上，提出了一种新的人体形态指数，该指数由身体表面积(BSA)、躯干垂直周长(VTC)、身高(H)和腰围(WC)四个人体测量指标构成。表面型身体形态指数(SBSI)定义为：SBSI与BMI、体重分别呈负相关，与腰围无相关性，与年龄呈一般线性关系。使用Cox比例模型和Kaplan-Meier曲线预测死亡风险的结果都表明，SBSI在预测全因死亡方面优于目前流行的身体形态指数(例如，BMI、WC、腰高比(WHtR)、腰臀比(WHR)、身体形态指数(ABSI))。我们将体型测量和体型测量结合起来，构建了一种新的人体测量方法--基于表面的体形指数(SBSI)。与其他流行的人体体型指数相比，SBSI通常与年龄呈线性关系，并随着死亡率的增加而增加。
Obesity is a global public health challenge. In the US, for instance, obesity prevalence remains high at more than one-third of the adult population, while over two-thirds are obese or overweight. Obesity is associated with various health problems, such as diabetes, cardiovascular diseases (CVDs), depression, some forms of cancer, sleep apnea, osteoarthritis, among others. The body mass index (BMI) is one of the best known measures of obesity. The BMI, however, has serious limitations, for instance, its inability to capture the distribution of lean mass and adipose tissue, which is a better predictor of diabetes and CVDs, and its curved (“U-shaped”) relationship with mortality hazard. Other anthropometric measures and their relation to obesity have been studied, each with its advantages and limitations. In this work, we introduce a new anthropometric measure (called Surface-based Body Shape Index, SBSI) that accounts for both body shape and body size, and evaluate its performance as a predictor of all-cause mortality. We analyzed data on 11,808 subjects (ages 18–85), from the National Health and Human Nutrition Examination Survey (NHANES) 1999–2004, with 8-year mortality follow up. Based on the analysis, we introduce a new body shape index constructed from four important anthropometric determinants of body shape and body size: body surface area (BSA), vertical trunk circumference (VTC), height (H) and waist circumference (WC). The surface-based body shape index (SBSI) is defined as follows: SBSI has negative correlation with BMI and weight respectively, no correlation with WC, and shows a generally linear relationship with age. Results on mortality hazard prediction using both the Cox proportionality model, and Kaplan-Meier curves each show that SBSI outperforms currently popular body shape indices (e.g., BMI, WC, waist-to-height ratio (WHtR), waist-to-hip ratio (WHR), A Body Shape Index (ABSI)) in predicting all-cause mortality. We combine measures of both body shape and body size to construct a novel anthropometric measure, the surface-based body shape index (SBSI). SBSI is generally linear with age, and increases with increasing mortality, when compared with other popular anthropometric indices of body shape.