Malignant vascular tumors in children and adolescents: A report from the Italian and German Soft Tissue Sarcoma Cooperative Group
Malignant vascular tumors in children and adolescents: A report from the Italian and German Soft Tissue Sarcoma Cooperative Group
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DOI：
10.1002/mpo.10078
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发表时间：
2002-08-01
期刊：
影响因子：
--
通讯作者：
Carli, M
中科院分区：
文献类型：
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作者：
Ferrari, A;Casanova, M;Carli, M
背景。恶性血管肿瘤在儿童时期极为罕见，其临床治疗资料也很少。我们报告了从1980年到2000年由意大利和德国软组织肉瘤合作小组治疗的18例恶性血管肿瘤儿童。过程。12例为血管肉瘤，4例为恶性血管内皮瘤，2例为卡波西氏肉瘤。手术切除6例；放疗6例，化疗14例。结果。中位随访208个月后，5年生存率和无事件生存率分别为30.9%和20.8%。6例患者存活，4例首次缓解（3例肿瘤）
Background. Malignant vascular tumors are extremely rare in childhood and few data on their clinical management are available. We report on a series of 18 children who had malignant vascular tumors, treated from 1980 to 2000 by the Italian and German Soft Tissue Sarcoma Cooperative Group. Procedure. Twelve patients had angiosarcoma, four had malignant hemangioendothelioma, and two had Kaposi's sarcoma. Surgical resection was completed in six cases; radiotherapy was administered to 6 children, and chemotherapy to 14. Results. After a median follow-up of 208 months, the 5-year survival and event-free survival rates were 30.9 and 20.8%. Six patients were alive, four in first remission (three had tumor