Coronary heart disease mortality trends in men in the post World War II birth cohorts aged 35-44 in Japan, South Korea and Taiwan compared with the United States
Coronary heart disease mortality trends in men in the post World War II birth cohorts aged 35-44 in Japan, South Korea and Taiwan compared with the United States
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DOI：
10.1093/ije/28.6.1044
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发表时间：
1999-12-01
影响因子：
7.7
通讯作者：
Pan, WH
中科院分区：
文献类型：
--
作者：
Sekikawa, A;Kuller, LH;Pan, WH
自第二次世界大战以来，日本、韩国和台湾的人们已经接触到了西方化的生活方式。最有可能的是，二战后的人群（1950年以上）受到的影响更大。我们假设在这些国家35-44岁的男性中冠心病（CHD）死亡率会增加。方法与结果韩国、台湾35 ~ 44岁男性冠心病死亡率近期呈上升趋势，日本呈下降趋势。日本35-44岁男性冠心病死亡率低于韩国和台湾，比美国低得多。国家样本数据和几项流行病学研究表明，在过去十年中，日本和美国的年轻成年男性冠心病的危险因素包括高胆固醇血症和高血压并没有太大差异。基于这些危险因素，日本和美国二战后冠心病人群的死亡率应该相似。然而，在美国，年龄在35-44岁的男性中，这一比例要高出5倍。在日本，这一年龄组的男性中，大多数死于心脏疾病的是心力衰竭；心力衰竭的死亡率大约是冠心病死亡率的三倍。在美国，35-44岁的男性很少使用心力衰竭。结论日本年轻男性冠心病死亡率持续较低可能是人为因素。二战后日本出生人群的冠心病死亡率可能与美国相似。
Background Since World War II, people in Japan, South Korea, and Taiwan have been exposed to a westernized lifestyle. It is most likely that the post World War II cohorts (1950+) have been more exposed. We hypothesize that there would be an increase in mortality from coronary heart disease (CHD) in men aged 35-44 in these countries.Methods and Results Mortality from CHD in men aged 35-44 in South Korea and Taiwan has recently increased, and in Japan it has decreased. Mortality from CHD in men aged 35-44 is lower in Japan than in either South Korea or Taiwan, and much lower than in the US. National sample data and several epidemiological studies have shown that risk factors for CHD including hypercholesterolaemia and hypertension in the past decade were not much different between young adult men in Japan and the US. Based upon these risk factors, CHD death rates among post World War II cohorts should be similar in Japan and the US. However, the rates are five times higher in the US for men aged 35-44. The majority of deaths in the category of diseases of the heart were from heart failure in men in this age group in Japan; the mortality from heart failure was about three times higher than the mortality from CHD. Heart failure was rarely used in men aged 35-44 in the US.Conclusions The continued low mortality rates from CHD in young men in Japan may be an artifact. II is possible that CHD death rates in post World War II birth cohort in Japan are similar to US rates.