The molecular basis of retinoic acid induced night blindness.
The molecular basis of retinoic acid induced night blindness.
复制标题
视黄酸诱导夜盲症的分子基础。
DOI:
10.1016/0006-291x(89)92674-0
复制
发表时间:
1989
影响因子:
3.1
通讯作者:
Rando,RR
中科院分区:
文献类型:
--
作者:
Law,WC;Rando,RR
Drugs which affect the processing of vitamin A in the retina or pigment epithelium can cause ocular toxicity. It is shown here that the retinoic acids, which are used in the treatment of skin disorders and which cause night blindness, inhibit the ocular retinol dehydrogenases in an in vitro system. This is shown to lead to a decrease in the formation of the visual chromophore 11-cis-retinal, thus explaining why night blindness might occur.
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影响因子:
2.9
作者:
Fulton,BS;Rando,RR
通讯作者:
Rando,RR
DOI:
--
发表时间:
1987
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Bernstein,PS;Law,WC;Rando,RR
通讯作者:
Rando,RR
影响因子:
--
作者:
R. Weleber;S. Denman;Jon M. Hanifin;William J. Cunningham
通讯作者:
William J. Cunningham
影响因子:
5.2
作者:
N. Raskin;K. Sligar;R. H. Steinberg
通讯作者:
R. H. Steinberg
影响因子:
2.9
作者:
BERNSTEIN, PS;RANDO, RR
通讯作者:
RANDO, RR