RECURRENT RECTAL-CANCER AND SCAR DIFFERENTIATION WITH PET AND MR IMAGING
RECURRENT RECTAL-CANCER AND SCAR DIFFERENTIATION WITH PET AND MR IMAGING
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DOI：
10.1148/radiology.182.2.1732979
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发表时间：
1992-02-01
期刊：
影响因子：
19.7
通讯作者：
SAKUMA, S
中科院分区：
文献类型：
--
作者：
ITO, K;KATO, T;SAKUMA, S
探讨正电子发射断层扫描（PET）和磁共振成像（MR）在直肠癌术后复发与瘢痕鉴别诊断中的价值。 对15例疑似复发的患者进行了18氟脱氧葡萄糖（FDG）PET和MR成像。 通过微分吸收比（DAR）测量质量中的FDG积累。 所有11例确诊为复发性直肠癌的患者肿块中FDG积聚增加（DAR = 4.73 +/- 2.28）。 在其余4例患者中观察到肿块中低FDG积聚（DAR = 0.97 +/- 0.15），其中瘢痕的存在通过有或无活检的随访观察来证实。 在MRI上，除1例外，其余均能与瘢痕相鉴别。 T2加权像上复发肿瘤和瘢痕的病灶-肌肉信号强度比分别为2.18 +/- 0.55和0.89 +/- 0.30。 PET和MR在直肠癌术后复发与瘢痕的鉴别诊断中具有互补性。 PET也可以允许评估治疗的效果。
The value of positron emission tomography (PET) and magnetic resonance (MR) imaging in differentiating recurrent rectal cancer and scar was investigated. PET with fluorine-18 2-fluoro-2-deoxy-D-glucose (FDG) and MR imaging were performed in 15 patients with suspected recurrence. FDG accumulation in the mass was measured by means of the differential absorption ratio (DAR). All 11 patients with confirmed recurrent rectal cancer had increased accumulation of FDG in the mass (DAR = 4.73 +/- 2.28). Low FDG accumulation in the mass (DAR = 0.97 +/- 0.15) was noted in the remaining four patients, in whom the presence of a scar was proved by means of follow-up observation with or without biopsy. On the MR images, the recurrent tumor could be differentiated from scar in all but one case. The lesion-muscle signal intensity ratios on the T2-weighted images for the recurrent tumor and scar were 2.18 +/- 0.55 and 0.89 +/- 0.30, respectively. PET and MR imaging complement each other in the differential diagnosis between recurrent rectal cancer and scar. PET may also permit the evaluation of the effect of therapy.