Clarification on the categorization of comorbidities.
Clarification on the categorization of comorbidities.
复制标题
澄清合并症的分类。
DOI：
10.1016/j.leukres.2009.08.036
复制
发表时间：
2010
影响因子：
2.7
通讯作者：
Ma,Xiaomei
中科院分区：
文献类型：
--
作者：
Wang,Rong;Ma,Xiaomei
Comorbidities are coexisting diseases that are distinct from the primary illness for which a patient seeks health care services 1. Comorbidity may affect detection, prognosis, therapy, and outcome of the primary disease. We recently published a paper evaluating the role of comorbidities in the survival of patients with myelodysplastic syndromes, in which Charlson index was utilized as the measure of comorbidities 2.Charlson et al. developed a weighted index measure of comorbidities based on medical records review and identified a total of 19 conditions that influence mortality 3. Both the number and the seriousness of comorbid conditions were taken into account. Each of the 19 conditions was assigned a weight (0-6) according to its potential for influencing mortality. A patient's comorbidity index would be the sum of all weighted comorbidities. A higher score on the Charlson index indicates a greater burden of comorbid conditions. Later, Deyo et al. adapted the Charlson index for use with the ICD-9-CM diagnostic and procedure codes available in administrative datasets 4. Researchers at the National Cancer Institute subsequently developed a SAS macro to calculate Charlson index for linked SEER* Medicare data (http://healthservices. cancer. gov/seermedicare/program/comorbidity. html). We adopted this method to calculate Charlson index for the more than 2,000 patients included in our study.
