PHOTOELECTRON ENHANCEMENT OF THE ABSORBED DOSE FROM X-RAYS TO HUMAN-BONE MARROW - EXPERIMENTAL AND THEORETICAL-STUDIES

PHOTOELECTRON ENHANCEMENT OF THE ABSORBED DOSE FROM X-RAYS TO HUMAN-BONE MARROW - EXPERIMENTAL AND THEORETICAL-STUDIES
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DOI:
10.1259/0007-1285-58-688-345
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发表时间:
1985-01-01
影响因子:
2.6
通讯作者:
SPIERS, FW
SPIERS, FW
中科院分区:
医学3区
文献类型:
--
作者:
KING, SD;SPIERS, FW

文献摘要

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本文介绍了一种将氟化锂粉末引入人骨小梁标本的骨髓腔中,以测定骨在20keV-140keV能量的X射线照射下对骨髓的过量光电子剂量的技术。对三个骨体积分数分别为10%、15%和25%的骨小梁标本进行了研究,并与早期Whitwell对单能电子的计算结果进行了比较。虽然有一些迹象表明,在较高的光子能量下,散射影响了实际测量,但实验结果和理论结果是合理一致的。然后,使用理论计算从骨标本上的测量结果推导出完整骨骼的光电子剂量增强,并计算出44岁、9岁和1.7岁受试者整个骨骼的平均骨髓剂量增强。
A technique is described by which lithium fluoride powder is introduced into the marrow cavities in specimens of human trabecular bone to determine the excess photoelectron dose to marrow, when bone is irradiated by X-rays of energies between 20 keV-140 keV. Three specimens of trabecular bone, containing respectively 10%, 15% and 25% bone by volume, were investigated and the results compared with those derived on the basis of earlier calculations for mono-energetic electrons by Whitwell. Reasonable agreement was found between the experimental and theoretical results, although there was some indication that scatter influenced the practical measurements at the higher photon energies. Theoretical calculations are then used to derive photoelectron dose enhancements for complete bones from the measured results on the bone specimens and mean enhancements of the marrow dose for the whole human skeleton are calculated for subjects aged 44, 9 and 1.7 yr.