Relationship between catecholamines and serotonin in sympathetic nerves of the rat pineal gland.

Relationship between catecholamines and serotonin in sympathetic nerves of the rat pineal gland.
复制标题

大鼠松果体交感神经儿茶酚胺和血清素的关系。

DOI:
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发表时间:
1969
期刊:
Journal of Neurobiology
影响因子:
--
通讯作者:
J. Axelrod
J. Axelrod
中科院分区:
--
文献类型:
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作者:
M. Zweig;J. Axelrod

文献摘要

被引文献

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Sympathetic nerves of the pineal gland contain both serotonin and norepinephrine. Inhibition of norepinephrine synthesis with a tyrosine hydroxylase inhibitor, α-methyl-p-tyrosine (αMPT), causes an elevation of pineal serotonin. The administration of dopamine or norepinephrine blocks the elevation of pineal serotonin by αMPT. When sympathetic nerves to the pineal are interrupted αMPT no longer causes a rise in pineal serotonin. Tryptophan causes a marked increase in pineal serotonin; αMPT enhances and norepinephrine blocks this rise.