Agreement between responses to a standardized asthma questionnaire and a questionnaire following a demonstration of asthma symptoms in adults
Agreement between responses to a standardized asthma questionnaire and a questionnaire following a demonstration of asthma symptoms in adults
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DOI：
10.1093/aje/kwj052
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发表时间：
2006-02-15
影响因子：
5
通讯作者：
Diaz, PV
中科院分区：
文献类型：
--
作者：
Smeeton, NC;Rona, RJ;Diaz, PV
哮喘流行病学在很大程度上依赖于标准化的问卷调查，但对社区成年人对哮喘症状的理解知之甚少。2004年，作者评估了标准化问卷的回答与参与者在观看哮喘症状演示后完成的问卷的回答之间的一致性水平。这项研究涉及来自智利的601名年轻人。现场工作人员接受培训，向参与者解释和演示哮喘症状。症状为喘息、夜间醒来呼吸困难、运动后呼吸困难和醒来咳嗽。Kappa统计量不超过0.4，演示后记录的哮喘症状患病率比标准化问卷低30-60%。以支气管反应性作为替代金标准，喘息和清醒时呼吸短促的阳性似然比在症状出现后更高。标准化问卷和示范后问卷之间的低一致性以及标准化问卷的似然比接近1降低了作者对该工具用于估计社区哮喘患病率的适当性的信心。对于哮喘的病因学研究，这可能导致分析相同病因暴露的不同研究之间缺乏一致性。
Asthma epidemiology relies heavily on standardized questionnaires, but little is known about the understanding of asthma symptoms among adults in the community. In 2004, the authors assessed the level of agreement between responses to a standardized questionnaire and responses to a questionnaire completed by participants after viewing a demonstration of asthma symptoms. The study involved 601 young adults from Chile. The field-workers were trained to explain and demonstrate the asthma symptoms to the participants. The symptoms were wheeze, waking at night with breathlessness, breathlessness following exercise, and waking with cough. The kappa statistic did not exceed 0.4, and the recorded prevalence of asthma symptoms following the demonstration was 30-60% lower than that for the standardized questionnaire. Using bronchial responsiveness as the proxy gold standard, the positive likelihood ratios for wheeze and waking short of breath were higher following symptom demonstration. The low agreement between the standardized questionnaire and the postdemonstration questionnaire and the likelihood ratios' closeness to 1 for the standardized questionnaire decreases the authors' confidence in the appropriateness of this tool for estimating the prevalence of asthma in the community. For etiologic studies of asthma, it may contribute to the lack of consistency between different studies analyzing the same etiologic exposures.