Concentrations of PGF-2 alpha and PGE-2 in the uterine venous blood of rabbits during pseudopregnancy and pregnancy.
Concentrations of PGF-2 alpha and PGE-2 in the uterine venous blood of rabbits during pseudopregnancy and pregnancy.
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假孕和妊娠期间家兔子宫静脉血中PGF-2α和PGE-2的浓度。
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
N. Poyser
中科院分区：
文献类型：
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作者：
F. Lytton;N. Poyser
从第14天开始，完整和子宫切除假孕兔的外周血浆孕酮浓度下降。在第17天，完整兔的降低速率加快，但在子宫切除兔中未加速，并与子宫静脉血浆中PGF-2 α水平的增加相关。子宫PGE-2分泌量在假孕过程中无变化。在妊娠兔中，外周血浆孕酮浓度在第30天仍然很高，第17天子宫静脉血浆PGF-2 α水平没有增加，妊娠第25天子宫静脉血浆PGF-2 α水平升高，但血浆孕酮浓度没有同时下降。子宫静脉血浆中PGE-2水平在妊娠第11天后显著增加，并且在一些兔中达到非常高的浓度。
Peripheral plasma progesterone concentrations in intact and hysterectomized pseudopregnant rabbits decreased from Day 14. The rate of decrease in intact, but not in hysterectomized, rabbits accelerated on Day 17 and was associated with an increase in PGF-2 alpha levels in the uterine venous plasma. There was no change in uterine PGE-2 output during pseudopregnancy. In pregnant rabbits, peripheral plasma progesterone concentrations remained high up to Day 30, and there was no increase in uterine venous plasma levels of PGF-2 alpha on Day 17, PGF-2 alpha levels were elevated in uterine venous plasma on Day 25 of pregnancy, but there was no concurrent decline in plasma progesterone concentrations. Uterine venous plasma levels in PGE-2 increased markedly after Day 11 of pregnancy and reached very high concentrations in some rabbits.