Adenovirus Core Proteins: Structure and Function.
Adenovirus Core Proteins: Structure and Function.
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DOI:
10.3390/v13030388
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发表时间:
2021-02-28
期刊:
影响因子:
--
通讯作者:
Tikoo SK
中科院分区:
文献类型:
--
作者:
Kulanayake S;Tikoo SK
Adenoviruses have served as a model for investigating viral-cell interactions and discovering different cellular processes, such as RNA splicing and DNA replication. In addition, the development and evaluation of adenoviruses as the viral vectors for vaccination and gene therapy has led to detailed investigations about adenovirus biology, including the structure and function of the adenovirus encoded proteins. While the determination of the structure and function of the viral capsid proteins in adenovirus biology has been the subject of numerous reports, the last few years have seen increased interest in elucidating the structure and function of the adenovirus core proteins. Here, we provide a review of research about the structure and function of the adenovirus core proteins in adenovirus biology.
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