Uterine sarcoma: Can it be differentiated from uterine leiomyoma with Doppler ultrasonography? A preliminary report
Uterine sarcoma: Can it be differentiated from uterine leiomyoma with Doppler ultrasonography? A preliminary report
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DOI：
10.1046/j.1469-0705.1997.09020101.x
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发表时间：
1997-02-01
影响因子：
7.1
通讯作者：
Hirai, M
中科院分区：
文献类型：
--
作者：
Hata, K;Hata, T;Hirai, M
我们的目的是评估瘤内血流分析是否可以区分子宫肉瘤和子宫平滑肌瘤。回顾性分析了41例经组织学证实的子宫平滑肌瘤和5例子宫肉瘤（4例平滑肌肉瘤，1例混合性中胚层肿瘤）的彩色和脉冲多普勒表现。记录瘤内血流速度波形，计算阻力指数（RI）和收缩期峰值血流速度（PSV），子宫平滑肌瘤RI（中位数0.647，范围0.422-0.896）与子宫肉瘤RI（中位数0.663，范围0.330-0.774）差异无统计学意义。子宫肉瘤的PSV（中位数61.6cm/s，范围40.0- 124.0cm/s）明显高于子宫肌瘤（中位数21.6cm/s，范围6.3- 48.6cm/s）（p < 0.05）。当PSV的截断值为41.0 cm/s（子宫肌瘤的平均PSV加上2个标准差）时，子宫肉瘤的检出率为80.0%，假阳性率为2.4%。提示彩色及脉冲多普勒超声检测肿瘤内PSV有助于子宫肉瘤的术前鉴别诊断。
Our objective was to evaluate whether intratumoral blood flow analysis could differentiate uterine sarcoma from uterine leiomyoma. Color and pulsed Doppler findings obtained from 41 patients with histologically proven uterine leiomyoma and five with uterine sarcoma (four leiomyosarcoma, one mixed mesodermal tumor) were retrospectively assessed. Intratumoral blood flow velocity waveforms were recorded, and the resistance index (RI) and peak systolic velocity (PSV) were calculated.There was no significant difference between the RI (median 0.647; range 0.422-0.896) in the uterine leiomyomas and the RI (median 0.663; range 0.330-0.774) in the uterine sarcomas. The PSV (median 61.6 cm/s; range 40.0-124.0 cm/s) in the uterine sarcomas was significantly higher (median 21.6 cm/s, range 6.3-48.6 cm/s) than that in the uterine leiomyomas (p < 0.05). When a cut-off value for the PSV of 41.0 cm/s (mean PSV of the uterine leiomyomas plus 2 standard deviations) was considered, the detection rate for uterine sarcoma was 80.0%, and the false-positive rate was 2.4%. These results suggest that the PSV within the tumor detected by color and pulsed Doppler ultrasonography could be useful for the preoperative differential diagnosis of uterine sarcoma.