Palmaz stent in the treatment of central venous stenosis: safety and efficacy of redilation.
Palmaz stent in the treatment of central venous stenosis: safety and efficacy of redilation.
复制标题
Palmaz 支架治疗中心静脉狭窄：再扩张的安全性和有效性。
DOI：
10.1148/radiology.190.2.8284384
复制
发表时间：
1994
期刊：
影响因子：
19.7
通讯作者：
OstermanJr,FA
中科院分区：
文献类型：
--
作者：
Trerotola,SO;Lund,GB;Samphilipo,MA;Magee,CA;Newman,JS;Olson,JL;Anderson,JH;OstermanJr,FA
目的在生长动物模型中评估中心静脉支架再扩张的安全性和有效性。材料和方法将Palmaz支架放置在18只新生羔羊的下腔静脉（IVC）中。5个月后，进行腔静脉造影。支架附近IVC生长和/或新生内膜增生导致狭窄的动物被视为再扩张的候选动物。术后2个月或6个月复查腔静脉造影、血管内超声和组织学检查，13只动物的髂胫前动脉狭窄> 20%。进行了再扩张，支架直径平均增加了50%。无即刻并发症。晚期并发症包括非闭塞性层流凝块（n = 2）和组织条分裂但未闭塞腔静脉腔（n = 1）。所有支架均出现中度新生内膜增生。支架压缩（无关的再扩张）发生在7 animals.CONCLUSIONPalmaz支架可以安全有效地再扩张在动物模型中的生长中心静脉。
PURPOSETo assess the safety and efficacy of redilation of central venous stents in a growing animal model.MATERIALS AND METHODSPalmaz stents were placed in the inferior vena cava (IVC) in 18 newborn lambs. After 5 months, vena cavography was performed. Those animals in which growth of the IVC adjacent to the stent and/or neointimal hyperplasia had resulted in a stenosis were considered candidates for redilation. Repeat vena cavography, intravascular ultrasound, and histologic examination were performed at 2 or 6 months.RESULTSA stenosis of > 20% was demonstrated in 13 animals. Redilation was performed, and a 50% mean increase in stent diameter was achieved. There were no immediate complications. Late complications included nonocclusive laminar clot (n = 2), and a bar of tissue dividing but not occluding the caval lumen (n = 1). Moderate neointimal hyperplasia occurred in all stents. Stent compression (unrelated to redilation) occurred in seven animals.CONCLUSIONPalmaz stents can be redilated safely and effectively in an animal model of growing central veins.