High-Resolution Mapping of VentricularScar: Evaluation of a Novel Integrated Multielectrode Mapping andAblation Catheter.
High-Resolution Mapping of VentricularScar: Evaluation of a Novel Integrated Multielectrode Mapping andAblation Catheter.
复制标题
DOI：
10.1016/j.jacep.2016.12.016
复制
发表时间：
2017-03-01
期刊：
影响因子：
--
通讯作者：
Anter, Elad
中科院分区：
文献类型：
--
作者：
Leshem, Eran;Tschabrunn, Cory M;Anter, Elad
目的：本研究旨在评估一种研究导管，该导管包含沿标准 3.5 毫米开放式冲洗导管圆周嵌入的 3 个微电极。背景：测绘分辨率受电极尺寸和电极间间距的影响。与标准消融导管相比，多电极标测导管提高了疤痕内的标测分辨率；然而，这需要使用 2 根独立的导管进行标测和消融。 方法：使用 THERMOCOOL SMARTTOUCH SF 导管（Qdot，Biosense Webster，Diamond Bar，California）对 6 只已治愈的梗塞猪和 2 只健康对照猪进行左心室标测，该导管的圆周上有 3 个额外的微电极 (0.167 mm2)。使用电图特征、心脏磁共振和组织学比较了标准电极和微电极在健康组织和疤痕组织中的标测分辨率。 结果：在健康心肌中，标准电极和微电极之间的双极电压幅度相似，第五百分位数分别为 1.19 和 1.30 mV。在治愈的梗塞中，低双极电压区域（定义为
OBJECTIVES: This study sought to evaluate an investigational catheter that incorporates 3 microelectrodes embedded along the circumference of a standard 3.5-mm open-irrigated catheter.BACKGROUND: Mapping resolution is influenced by both electrode size and interelectrode spacing. Multielectrode mapping catheters enhance mapping resolution within scar compared with standard ablation catheters; however, this requires the use of 2 separate catheters for mapping and ablation.METHODS: Six swine with healed infarction and 2 healthy controls underwent mapping of the left ventricle using a THERMOCOOL SMARTTOUCH SF catheter with 3 additional microelectrodes (0.167 mm2) along its circumference (Qdot, Biosense Webster, Diamond Bar, California). Mapping resolution in healthy and scarred tissue was compared between the standard electrodes and microelectrodes using electrogram characteristics, cardiac magnetic resonance, and histology.RESULTS: In healthy myocardium, bipolar voltage amplitude was similar between the standard electrodes and microelectrodes, with a fifth percentile of 1.19 and 1.30 mV, respectively. In healed infarction, the area of low bipolar voltage (defined as