Complications of sclerotherapy for 75 head and neck venous malformations
Complications of sclerotherapy for 75 head and neck venous malformations
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DOI：
10.1007/s00405-015-3577-x
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发表时间：
2016-04-01
影响因子：
2.6
通讯作者：
Pitkaranta，Anne
中科院分区：
文献类型：
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作者：
Castren，Eeva;Aronniemi，Johanna;Pitkaranta，Anne
硬化疗法是头颈部静脉畸形(VM)的一种治疗选择。然而，对并发症风险的评估对于提高其安全性是至关重要的。我们的目标是通过Clavien-Dindo分类系统地报告硬化治疗并发症，并区分易发生并发症的因素。我们确定了我们机构在2007年1月1日至2013年8月31日期间接受硬化治疗的头颈部VM患者，回顾分析了患者报告，并对他们应用了Clavien-Dindo分类。我们的75名VM患者总共接受了150次硬化治疗。最常见的硬化剂是3%十四烷基硫酸钠和聚多糖醇。并发症发生13例(17.3%)，15次(10.0%)；3例需要广泛的术后治疗，导致永久性并发症，12例接受保守治疗。有硬化治疗并发症的患者接受了更多的治疗(p=0.009)，并且更多地需要进一步手术(p=0.007)。因此，我们认为硬化疗法是一种相对安全的头颈部VM治疗方法。为了避免并发症，在多学科团队中评估VM的特征和最佳治疗技术是至关重要的。
Sclerotherapy is one treatment option for head and neck venous malformations (VMs). Evaluation of complication risks is, however, essential to improve its safety. We aimed to systematically report sclerotherapy complications by means of the Clavien-Dindo classification and to distinguish factors predisposing to complications. We identified our institution’s head and neck VM patients who received sclerotherapy between 1 January 2007 and 31 August 2013, analyzed patient reports retrospectively, and applied to them the Clavien-Dindo classification. Our 75 VM patients underwent a total of 150 sclerotherapy sessions. The most common sclerosants were 3 % sodium tetradecyl sulfate and polidocanol. Complications occurred in 13 patients (17.3 %) and in 15 sessions (10.0 %); 3 complications required extensive postprocedural treatment and caused permanent morbidity, whereas 12 received conservative treatment. Patients with sclerotherapy complications underwent more treatments (p= 0.009) and more often needed further surgery (p= 0.007). We thus consider sclerotherapy a relatively safe treatment modality for head and neck VMs. To avoid complications, evaluation of VM characteristics and optimal treatment technique in a multidisciplinary team is vital.