CLINICAL AND SUBCLINICAL THIAMINE-DEFICIENCY IN CLINICAL-PRACTICE
CLINICAL AND SUBCLINICAL THIAMINE-DEFICIENCY IN CLINICAL-PRACTICE
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DOI：
10.1097/00002826-198509000-00010
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发表时间：
1985-01-01
影响因子：
1
通讯作者：
BARRY, S
中科院分区：
文献类型：
--
作者：
CARNEY, MWP;BARRY, S
描述了6例在英国正常精神科实践中发现的严重硫胺素缺乏症。两个调查新入院的精神病患者重新叙述。一个主要程度的生化缺陷，或没有最低限度的临床表现，被发现。只有三个（1%）的326名患者调查有严重的临床缺陷。据认为，严重的硫胺素缺乏症虽然在西方国家很少见，但尚未根除。缺乏可能导致精神疾病，如韦尼克脑病，或可能是由于厌食症，食物摄入量减少和营养不良引起的精神疾病的次要特征。强调了正确诊断的可能性的重要性。
Six patients with gross thiamine deficiency found during normal psychiatric practice in England are described. Two surveys of newly admitted psychiatric patients are recounted. A major degree of biochemical deficiency, with or without minimal clinical manifestations, was found. Only three (1%) of 326 patients surveyed had gross clinical deficiency. It is thought that severe thiamine deficiency, though rare in the Western countries, has not been eradicated. Deficiency may cause psychiatric conditions like Wernicke's encephalopathy or may be a secondary feature in mental illness due to anorexia, in reduced food intake, and in poor nutrition. The importance of being aware of the possibility for correct diagnosis is emphasised.