Low modulus and bioactive Ti/alpha-TCP/Ti-mesh composite prepared by spark plasma sintering
Low modulus and bioactive Ti/alpha-TCP/Ti-mesh composite prepared by spark plasma sintering
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放电等离子烧结制备低模量生物活性Ti/α-TCP/Ti-mesh复合材料
DOI：
10.1016/j.msec.2017.05.014
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Tang Hanchun
中科院分区：
文献类型：
--
作者：
Guo Yu;Tan Yanni;Liu Yong;Liu Shifeng;Zhou Rui;Tang Hanchun
采用放电等离子烧结技术制备了Ti/α-TCP颗粒填充的钛网状支架复合材料。用扫描电子显微镜(SEM)、能谱仪(EDS)和X射线衍射仪(X射线衍射仪)研究了复合材料的微观结构和界面反应。分别用模拟体液和细胞培养法评价材料的体外生物活性和生物相容性。高温烧结后，生成了钛的氧化物、TixPy和CaTiO3。钛氧化物和TixPy的形成是O和P元素从α-TcP向Ti扩散的结果。CaTiO_3是钛与α-TCP反应的产物。70Ti/α-TCP/钛网状复合材料具有较高的抗压强度(589 Gpa)和较低的压缩模数(30 Gpa)。生物活性测试显示，复合材料上形成了一层厚厚的磷灰石层，细胞附着均匀。良好的力学性能和生物活性表明，Ti/α-TcP/Ti-Mesh复合材料在骨科植入物中具有很高的应用潜力。
A titanium mesh scaffold composite filled with Ti/α-TCP particles was prepared by spark plasma sintering (SPS). The microstructures and interfacial reactions of the composites were investigated by scanning electron microscopy (SEM), Energy Dispersive Spectroscopy (EDS) and X-ray diffraction (XRD) analyses. The compressive strength and elastic modulus were also measured.In vitrobioactivity and biocompatibility was evaluated by using simulated body fluid and cells culture, respectively. After high temperature sintering, Ti oxides, TixPyand CaTiO3were formed. The formation of Ti oxides and TixPywere resulted from the diffusion of O and P elements from α-TCP to Ti. CaTiO3was the reaction product of Ti and α-TCP. The composite of 70Ti/α-TCP incorporated with Ti mesh showed a high compressive strength of 589 MPa and a low compressive modulus of 30 GPa. The bioactivity test showed the formation of a thick apatite layer on the composite and well-spread cells attachment. A good combination of mechanical properties and bioactivity indicated a high potential application of Ti/α-TCP/Ti-mesh composite for orthopedic implants.