Growth Hormone Producing Pituitary Adenoma Regrowing as Pituitary Adenoma with Neuronal Choristoma 14 Years after Tumor Removal
Growth Hormone Producing Pituitary Adenoma Regrowing as Pituitary Adenoma with Neuronal Choristoma 14 Years after Tumor Removal
复制标题
产生生长激素的垂体腺瘤在肿瘤切除 14 年后重新生长为伴有神经元分化瘤的垂体腺瘤
DOI：
10.1016/j.wneu.2012.06.031
复制
发表时间：
2012
期刊：
影响因子：
2
通讯作者：
Ogasawara K
中科院分区：
文献类型：
--
作者：
Sato Y;Wada T;Nishikawa Y;Yoshida K;Kurose A;Ogawa A;Ogasawara K
背景我们报告一例垂体腺瘤与神经元脉络膜瘤，通常是在最初的surgery.Case Description诊断一个50岁的女性肢端肥大症和双颞偏盲进行了切除垂体腺瘤通过经蝶入路的罕见协会。第一个手术标本的组织学检查显示只有腺瘤，这是嗜酸性和表达生长激素。14年后，双颞偏盲复发，磁共振成像显示残留tumor.DiscussionThe患者通过经蝶入路切除了再生肿瘤。第二次手术标本的组织学检查发现神经节细胞瘤和垂体腺瘤的一个小组件。ConclusionsThe本病例报告支持的理论，垂体腺瘤与神经元绒毛膜瘤可能代表神经元分化的结果从垂体腺瘤。
BackgroundWe report a case of an uncommon association of pituitary adenoma with neuronal choristoma that usually is diagnosed at initial surgery.Case DescriptionA 50-year-old woman with acromegaly and bitemporal hemianopsia underwent removal of a pituitary adenoma via the transsphenoidal approach. Histologic examination of the first surgical specimen demonstrated only adenoma, which was eosinophilic and expressed growth hormone. Fourteen years later, bitemporal hemianopsia recurred, and magnetic resonance imaging revealed regrowth of the residual tumor.DiscussionThe patient underwent removal of the regrown tumor via the transsphenoidal approach. Histologic examination of the second surgical specimen revealed gangliocytoma and a small component of pituitary adenoma.ConclusionsThe present case report supports the theory that pituitary adenoma with neuronal choristoma might represent the result of neuronal differentiation from pituitary adenoma.