Rapid vibrational imaging with sum frequency generation microscopy.
Rapid vibrational imaging with sum frequency generation microscopy.
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DOI：
10.1364/ol.36.003891
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发表时间：
2011-10-01
期刊：
影响因子：
3.6
通讯作者：
Potma EO
中科院分区：
文献类型：
--
作者：
Raghunathan V;Han Y;Korth O;Ge NH;Potma EO
我们展示了基于和频产生（SFG）显微镜与共线激发几何的快速振动成像。利用高重复率光学参量振荡器产生的可调谐皮秒脉冲，实现了胶原纤维的亚微米横向分辨率的振动选择性成像。此外，我们同时SFG和二次谐波产生成像，以强调与其他非线性光学模式的显微镜的兼容性。
We demonstrate rapid vibrational imaging based on sum frequency generation (SFG) microscopy with a collinear excitation geometry. Using the tunable picosecond pulses from a high-repetition-rate optical parametric oscillator, vibrationally selective imaging of collagen fibers is achieved with submicrometer lateral resolution. We furthermore show simultaneous SFG and second harmonic generation imaging to emphasize the compatibility of the microscope with other nonlinear optical modalities.