Biomedical membranes from hydrogels and interpolymer complexes

Biomedical membranes from hydrogels and interpolymer complexes
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DOI:
10.1007/3540587888_15
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发表时间:
1995-12
影响因子:
--
通讯作者:
C. L. Bell;N. Peppas
C. L. Bell;N. Peppas
中科院分区:
化学4区
文献类型:
--
作者:
C. L. Bell;N. Peppas

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水凝胶膜的生物医学应用需要了解其结构特征和扩散行为。因此,本综述的主题是分析这种生物膜对其周围环境的响应。这种响应行为可能是由于聚合物链上某些官能团的存在或聚合物链之间特定的相互作用(络合作用)。在膜应用中使用这些生理响应性材料时,这一行为尤其重要。我们首先介绍水凝胶膜的结构特征和行为,然后讨论水凝胶的环境响应行为类型。然后重点讨论聚合物间络合作用的主题,重点是氢键引起的络合作用,以及如何利用这种类型的行为来制造响应性膜。最后,对膜中的传输理论进行了综述。
Biomedical applications of hydrogel membranes require understanding of their structural characteristics and diffusive behavior. Thus, the subject of this review is the analysis of the response of such biomembranes to their surrounding environment. This responsive behavior may be due to the presence of certain functional groups along the polymer chains or specific interactions between polymer chains (complexation). This behavior is particularly important in the use of these physiologically responsive materials in membrane applications. We begin with an introduction to the structural characteristics and behavior of hydrogel membranes followed by a discussion of the types of environmentally responsive behavior seen with hydrogels. The subject of interpolymer complexation is then treated with emphasis on complexation due to hydrogen bonding and how this type of behavior may be used to produce responsive membranes. Finally, the theories of transport in membranes are reviewed.