Single Chain Self-Assembly of Well-Defined Heterotelechelic Polymers Generated by ATRP and Click Chemistry Revisited
Single Chain Self-Assembly of Well-Defined Heterotelechelic Polymers Generated by ATRP and Click Chemistry Revisited
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DOI：
10.1002/pola.24688
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发表时间：
2011-06-15
影响因子：
--
通讯作者：
Barner-Kowollik, Christopher
中科院分区：
文献类型：
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作者：
Altintas, Ozcan;Rudolph, Tobias;Barner-Kowollik, Christopher
携带胸腺嘧啶/二氨基吡啶（DAP）的明确杂遥爪聚苯乙烯（Mn，SEC 9300，PDI 1.04）和汉密尔顿楔形（HW）/氰尿酸（CA）（Mn，SEC 8200，PDI 1.04）键合基序通过受控/活性自由基聚合和铜催化的叠氮化物/炔“点击”化学的组合来制备，并且随后自组装为单链以模拟-在一个简单的水平上-天然生物大分子的自折叠行为。氘代二氯甲烷中的氢核磁共振（H-1 NMR）和动态光散射分析提供了胸腺嘧啶和ω-DAP以及杂遥爪聚合物的α-CA和ω-HW链端之间的氢键相互作用导致循环熵驱动的单链自组装的证据。本研究表明，NMR溶剂的选择是很重要的获得良好分辨的自组装结构的NMR谱。此外，对HW的空间效应可以影响自组装过程的效率。(C)2011 Wiley Periodicals，Inc.聚合物科学杂志A部分：聚合物化学49：2566-2576，2011
Well-defined heterotelechelic poly(styrene) carrying thymine/diaminopyridine (DAP) (Mn, SEC 9300, PDI 1.04) and Hamilton wedge (HW)/cyanuric acid (CA) (Mn, SEC 8200, PDI 1.04) bonding motifs are prepared via a combination of controlled/living radical polymerization and copper catalyzed azide/alkyne "click'' chemistry and are subsequently self-assembled as single chains to emulate-on a simple level-the self-folding behavior of natural biomacromolecules. Hydrogen nuclear magnetic resonance (H-1 NMR) in deuterated dichloromethane and dynamic light scattering analyses provides evidence for the hydrogen bonding interactions between the athymine and omega-DAP as well as alpha-CA and omega-HW chain ends of the heterotelechelic polymers leading to circular entropy driven single chain self-assembly. This study demonstrates that the choice of NMR solvent is important for obtaining well-resolved NMR spectra of the self-assembled structures. In addition, steric effects on the HW can affect the efficiency of the self-assembly process. (C) 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 49: 2566-2576, 2011