Prior knowledge is essential for the beneficial effect of targeted memory reactivation during sleep
Prior knowledge is essential for the beneficial effect of targeted memory reactivation during sleep
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DOI：
10.1038/srep39763
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发表时间：
2017-01-04
影响因子：
4.6
通讯作者：
Wilhelm, Ines
中科院分区：
文献类型：
--
作者：
Groch, Sabine;Schreiner, Thomas;Wilhelm, Ines
先验知识加速了系统整合，并加速了新获得的记忆整合到现有的新皮层知识网络中。通过使用有针对性的记忆再激活，我们证明了先验知识对于睡眠期间记忆的成功再激活和巩固也是必不可少的，无论是在行为水平还是振荡水平（即，θ和快速纺锤体活动）。因此，先验知识是睡眠期间新记忆进入系统巩固过程的先决条件。
Prior knowledge speeds up system consolidation and accelerates integration of newly acquired memories into existing neocortical knowledge networks. By using targeted memory reactivations, we demonstrate that prior knowledge is also essential for successful reactivation and consolidation of memories during sleep, both on the behavioral and oscillatory level (i.e., theta and fast spindle activity). Thus, prior knowledge is a prerequisite for new memories to enter processes of system consolidation during sleep.