The role of anabolic steroids on baseline and stress heart rate in cynomolgus monkeys.
The role of anabolic steroids on baseline and stress heart rate in cynomolgus monkeys.
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合成代谢类固醇对食蟹猴基线和应激心率的作用。
DOI：
10.1037/h0090266
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Manuck,SB
中科院分区：
文献类型：
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作者：
Rejeski,WJ;Brubaker,PH;Herb,RA;Kaplan,JR;Manuck,SB
本研究检查了合成代谢类固醇对食蟹猴基线心率（HR）和HR对捕获威胁的反应的作用。将10只食蟹猴随机分配至类固醇或假手术对照组。类固醇治疗的动物每两周注射一次睾酮，持续10周，而假手术对照组则按相同的时间表注射芝麻油。评估治疗前和治疗后HR，以建立基线和急性应激反应。结果显示，与假手术对照组相比，给予睾酮的动物的基线HR出现统计学显著性增加。在对捕获威胁的反应中，没有发现组间的差异。（PsycINFO数据库记录（c）2016阿帕，保留所有权利）
This investigation examined the role of anabolic steroids on baseline heart rate (HR) and HR responses to the threat of capture in Macaca fascicularis. Ten cynomolgus monkeys were randomly assigned either to a steroid or to a sham control group. Steroid-treated animals were given testosterone injections biweekly for 10 weeks, whereas sham controls received injections of sesame oil on an identical schedule. Pretreatment and posttreatment HRs were evaluated to establish both baseline and acute-stress responses. Results revealed that animals given testosterone experienced a statistically significant increase in baseline HR when contrasted with the sham controls. No difference between the groups was detected in response to the threat of capture.(PsycINFO Database Record (c) 2016 APA, all rights reserved)