Extracorporeal membrane oxygenation as a bridge to cardiac transplantation in a patient with cardiomyopathy and hemophilia A.
Extracorporeal membrane oxygenation as a bridge to cardiac transplantation in a patient with cardiomyopathy and hemophilia A.
复制标题
体外膜氧合作为心肌病和 A 型血友病患者心脏移植的桥梁。
DOI：
10.1007/s00134-003-1748-5
复制
发表时间：
2003
影响因子：
38.9
通讯作者：
Blume,ElizabethD
中科院分区：
文献类型：
--
作者：
Thiagarajan,RaviR;Roth,StephenJ;Margossian,Steven;Mackie,AndrewS;Neufeld,EllisJ;Laussen,PeterC;Forbess,JosephM;Blume,ElizabethD
ObjectiveTo report the use of extracorporeal membrane oxygenation (ECMO) as a bridge to cardiac transplantation in a patient with hemophilia A and dilated cardiomyopathy.DesignCase report.Interventions and resultsDuring ECMO factor VIII concentrate was administered to maintain a factor VIII level close to 50% of normal control both to decrease the risk of bleeding and to allow standard anticoagulation with heparin. The patient developed an inhibitor to exogenous factor VIII during hospitalization, which was successfully managed with a high-dose continuous infusion of factor VIII during ECMO, the transplant operation, and the postoperative period.ConclusionsWe report the successful use of ECMO as a bridge to cardiac transplantation in a patient with hemophilia A and low-level factor VIII inhibitors.
