Cobalt-catalyzed aerobic oxidative Povarov reaction of tertiary anilines with dihydrofuran for the synthesis of hexahydrofuroquinolines

Cobalt-catalyzed aerobic oxidative Povarov reaction of tertiary anilines with dihydrofuran for the synthesis of hexahydrofuroquinolines
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钴催化叔苯胺与二氢呋喃有氧氧化Povarov反应合成六氢呋喃喹啉

DOI:
10.1016/j.tetlet.2016.10.031
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发表时间:
2016-11-16
影响因子:
1.8
通讯作者:
Wang, Yajun
Wang, Yajun
中科院分区:
化学4区
文献类型:
--
作者:
Huo, Congde;Chen, Fengjuan;Wang, Yajun

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开发了一种简单高效的钴催化叔苯胺与二氢呋喃需氧氧化脱氢波瓦洛夫反应,用于合成六氢呋喃并[3,2-c]喹啉。单电子氧化反应在温和的条件下进行,仅需要简单的钴盐作为催化剂和分子氧作为末端氧化剂。 (C) 2016 Elsevier Ltd. 保留所有权利。
A simple and efficient cobalt-catalyzed aerobic oxidative dehydrogenative Povarov reaction of tertiary anilines with dihydrofuran has been developed for the synthesis of hexahydrofuro[3,2-c]quinolines. The one-electron-oxidation involved reaction is performed under mild conditions and only requires simple cobalt salts as a catalyst and dioxygen as a terminal oxidant. (C) 2016 Elsevier Ltd. All rights reserved.