Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions.
Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions.
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DOI：
10.1210/edrv.18.6.0321
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发表时间：
1997-12
影响因子：
20.3
通讯作者：
S. Rajaram;D. Baylink;S. Mohan
中科院分区：
文献类型：
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作者：
S. Rajaram;D. Baylink;S. Mohan
I.二、导言IGFBPs的特点III. IGFBPs的靶细胞作用调节IGF作用B。促进IGF在细胞外基质中的储存。发挥IGF非依赖性效应IV.生物体液中的IGF-IGFBP复合物A.血清B。米尔克角尿D。脑脊液E.卵泡液F.羊水G.淋巴H.精液I.其他生物流体V. IGFBP A循环水平的测定。蛋白质配体印迹法B。Western免疫印迹C. RIA D.免疫放射测定（IRMA）IGFBPs在血清中的相对分布VII.血清IGFBPs的调节A.生理条件B。发育与衰老C.激素效应：机制D。病理状况VIII.循环中的IGFBP蛋白酶A.正常条件下的蛋白酶B。妊娠相关蛋白酶C.分解代谢和疾病状态下的蛋白酶IX.血清IGFBPs的内分泌功能。预防胰岛素样作用B。增加IGFs C.为了控制交通...
I. Introduction II. Characteristics of the IGFBPs III. Target Cell Actions of the IGFBPs A. To modulate IGF actions B. To facilitate storage of IGFs in extracellular matrices C. To exert IGF-independent effects IV. IGF-IGFBP Complexes in Biological Fluids A. Serum B. Milk C. Urine D. Cerebrospinal fluid (CSF) E. Follicular fluid F. Amniotic fluid G. Lymph H. Seminal fluid I. Other biological fluids V. Assays for Circulating Levels of IGFBP A. Western ligand blotting B. Western immunoblotting C. RIA D. Immunoradiometric assay (IRMA) VI. Relative Distribution of IGFBPs in Serum VII. Regulation of Serum IGFBPs A. Physiological conditions B. Development and aging C. Hormonal effects: mechanisms D. Pathological conditions VIII. IGFBP Proteases in Circulation A. Proteases under normal conditions B. Pregnancy-associated proteases C. Proteases under catabolic and disease states IX. Endocrine Functions of IGFBPs in Serum A. To prevent insulin-like effects B. To increase the half-lives of IGFs C. To control the tra...