Score for Neonatal Acute Physiology: a physiologic severity index for neonatal intensive care.

Score for Neonatal Acute Physiology: a physiologic severity index for neonatal intensive care.
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新生儿急性生理学评分:新生儿重症监护的生理严重程度指数。

DOI:
10.1542/peds.91.3.617
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发表时间:
1993
期刊:
影响因子:
8
通讯作者:
D. Goldmann
D. Goldmann
中科院分区:
医学2区
文献类型:
--
作者:
D. Richardson;J. Gray;M. McCormick;Kathryn P. Workman;D. Goldmann

文献摘要

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新生儿重症监护室 (NICU) 的出生体重调整死亡率的巨大差异可能反映了人群疾病严重程度的差异。制定疾病严重程度衡量标准对于比较结果至关重要。新生儿急性生理学评分 (SNAP) 是根据三个 NICU 的 1643 例入院病例(114 例死亡)进行前瞻性开发和验证。 SNAP 对每个器官系统在最初 24 小时内最严重的生理紊乱进行评分。 SNAP 与出生体重的相关性很小,即使在狭窄的出生体重层内,也能高度预测新生儿死亡率。它能够将患者分为死亡率风险高 2 至 20 倍的组。它还与其他严重程度指标高度相关,包括护理工作量 (r = .59)、治疗强度 (r = .78)、医生对死亡风险的估计 (r = .65) 和住院时间 (R2 = .59)。 SNAP 是 NICU 研究的重要新工具。
The substantial variation in birth weight-adjusted mortality among neonatal intensive care units (NICUs) may reflect differences in population illness severity. Development of an illness severity measure is essential for comparisons of outcomes. The Score for Neonatal Acute Physiology (SNAP) was developed and validated prospectively on 1643 admissions (114 deaths) in three NICUs. SNAP scores the worst physiologic derangements in each organ system in the first 24 hours. SNAP showed little correlation with birth weight and was highly predictive of neonatal mortality even within narrow birth weight strata. It was capable of separating patients into groups with 2 to 20 times higher mortality risk. It also correlated highly with other indicators of severity including nursing workload (r = .59), therapeutic intensity (r = .78), physician estimates of mortality risk (r = .65), and length of stay (R2 = .59). SNAP is an important new tool for NICU research.