NEOSTRIATAL GABAERGIC INTERNEURONS CONTAIN NOS, CALRETININ OR PARVALBUMIN
NEOSTRIATAL GABAERGIC INTERNEURONS CONTAIN NOS, CALRETININ OR PARVALBUMIN
复制标题
DOI:
10.1097/00001756-199312000-00004
复制
发表时间:
1993-12-13
期刊:
影响因子:
1.7
通讯作者:
KAWAGUCHI, Y
中科院分区:
文献类型:
--
作者:
KUBOTA, Y;MIKAWA, S;KAWAGUCHI, Y
To reveal functional heterogeneity among GABAergic interneurones in rat neostriatum, we investigated: (1) whether nitric oxide synthase (NOS)- and calretinin-immunoreactive cells, like parvalbumin-immunoreactive cells, were also immunoreactive for 67 kD glutamic acid decarboxylase (GAD(67)) and GABA; (2) whether NOS cells, calretinin cells and parvalbumin cells belonged to separate populations or not. NOS cells, calretinin cells and parvalbumin cells all showed immunoreactivity for GAD(67) in colchicine-treated rats. Calretinin cells and parvalbumin cells were also immunoreactive for GABA. Only a few cells (0-3%) showed immunoreactivity for two antigens. These results suggest that the neostriatum has at least three GABAergic interneuronal systems.