Antioxidant flavonoid glycosides from Daphniphyllum calycinum
Antioxidant flavonoid glycosides from Daphniphyllum calycinum
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DOI：
10.1021/np9800203
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发表时间：
1998-05-01
影响因子：
5.1
通讯作者：
Kinghorn, AD
中科院分区：
文献类型：
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作者：
Gamez, EJC;Luyengi, L;Kinghorn, AD
从 Daphniphyllum calycinum 叶子的乙酸乙酯提取物中分离出一种新型黄酮二糖苷 5,6,7,4'-四羟基黄酮醇 3-O-芸香苷 (1) 和一种先前已知的化合物山奈酚 3-O-新橙皮苷 (2)，其在 1,1-二苯基-2-苦基肼 (DPPH) 自由基测定中显示出显着的活性。通过结合光谱方法阐明了 1 的结构，并且在 DPPH 测定中发现化合物 1 和 2 作为抗氧化剂具有中等活性。
A novel flavonoid diglycoside, 5,6,7,4'-tetrahydroxyflavonol 3-O-rutinoside (1), and a previously known compound, kaempferol 3-O-neohesperidoside (2), were isolated from an ethyl acetate extract of Daphniphyllum calycinum leaves that showed significant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assay. The structure of 1 was elucidated by a combination of spectroscopic methods, and compounds 1 and 2 were found to be moderately active as antioxidants in the DPPH assay.