EXPERIMENTAL STUDIES ON CONNECTIVE-TISSUE OF CAPSULAR LIGAMENT - INFLUENCES OF AGING AND SEX-HORMONES
EXPERIMENTAL STUDIES ON CONNECTIVE-TISSUE OF CAPSULAR LIGAMENT - INFLUENCES OF AGING AND SEX-HORMONES
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DOI：
10.3109/17453677608988723
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发表时间：
1976-01-01
期刊：
影响因子：
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通讯作者：
TAKEDA, T
中科院分区：
文献类型：
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作者：
HAMA, H;YAMAMURO, T;TAKEDA, T
研究了衰老和性激素对Wistar大鼠髋关节囊结缔组织代谢的生化和形态学影响。随着年龄的增长，两性髋关节囊的胶原含量和胶原纤维直径逐渐增加，直至性成熟。性成熟后，雄性的胶原蛋白含量明显高于雌性。切除卵巢的雄性大鼠胶原蛋白含量和纤维直径显著增加，雌激素或雌激素与黄体酮联合使用的大鼠胶原蛋白含量和纤维直径显著降低，而睾丸激素则显著增加。
Influences of aging and sex hormones on connective tissue metabolism in the hip joint capsule of Wistar rats were analyzed biochemically and morphologically. As age advanced, collagen content and collagen fibril diameter of the hip joint capsule increased gradually in both sexes until sexual maturation was reached. Collagen content was significantly greater in males than in females after sexual maturation. Collagen content and fibril diameter were considerably increased by ovariectomy and significantly decreased by the administration of estrogen, or estrogen combined with progesterone, whereas they were significantly increased by the administration of testosterone in orchiectomized male rats.